Project 4 - Modulation of the Renal Fibrogenic Response by Cathepsins

This page document is being viewed within the PCEN Projects collection.

Last modified on January 23, 2012 at 1:27 PM by Dominique Brand

Summary description:

Project Director: Allison Eddy, M.D.

Consultant: Scott Turner, Ph.D.

CKD is a major risk factor for cardiovascular disease (5x increased risk).  An estimated 28 million adult Americans have CKD; a subset (currently > 500,000) will survive long enough to need dialysis or a kidney transplant.  At this time, no therapy is known to have a clinically significant impact on CKD progression rates.  The goal of the proposed research is to develop a scientific foundation and rationale for new CKD therapies.