Project 4 - Modulation of the Renal Fibrogenic Response by Cathepsins
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Summary description:
Project Director: Allison Eddy, M.D.
Consultant: Scott Turner, Ph.D.
CKD is a major risk factor for cardiovascular disease (5x increased risk). An estimated 28 million adult Americans have CKD; a subset (currently > 500,000) will survive long enough to need dialysis or a kidney transplant. At this time, no therapy is known to have a clinically significant impact on CKD progression rates. The goal of the proposed research is to develop a scientific foundation and rationale for new CKD therapies.


