Stacey Huppert
Assistant Professor of Cell and Developmental Biol
Huppert Lab
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Stacey S Huppert, Ph.D. - Profile

Research Profile

Dr. Stacey S. Huppert joined the Vanderbilt Center for Stem Cell Biology (VCSCB) in October of 2005 as its first faculty recruit.  Stacey earned her doctorate in genetics from Indiana University in the Laboratory of Marc A. T. Muskavitch.  Her thesis work demonstrated that Notch signaling exerts feedback regulation on ligand and receptor expression, and that the resultant asymmetries underlie proper cell fate determination.  She continued to study Notch signaling mechanisms with Raphael Kopan, first as a postdoctoral fellow, then as an Instructor in the Department of Molecular Biology and Pharmacology at Washington University School of Medicine.  Dr. Huppert’s research program will focus on exploring how intercellular signaling pathways are integrated in both developmental and disease responses of the liver.  She will explore the role of Notch in liver organogenesis and regeneration in order to better understand the role of progenitor/stem cells in hepatocyte cell population maintenance and renewal.

Research Keywords

developmental biology, stem cell biology, genetics, cell signaling, signal transduction, cell fate determination, cancer, mouse knockouts and transgenics, embryonic stem cell differentiation, organ cultures, liver regeneration, liver disease, notch pathway

Publications

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