Randy Blakely, Ph.D. - Profile


The Center for Molecular Neuroscience
View member profile

465 21st Avenue South
7150 MRB III
Nashville, TN, United States, 37232
Phone: (615) 936-1700
Fax: (615) 936-3745


Research Profile

My laboratory explores the molecular basis for neurotransmitter transporter structure, function and regulation. We use chimera, site-directed mutagenesis and site-specific chemical modification strategies to explore the topology and quaternary structure of biogenic amine transporters. We are evaluating what molecules control the proper localization and activity of transporter proteins using genetic (C.elegans), and molecular biologic methods. We are also evaluating whether human transporter polymorphisms impact the biosynthesis, trafficking and function of transporters and confer increased risk for autonomic, neurologic and mental disorders.

Research Keywords

pharmacology, Psychiatry, neurotransmitter, transport, genetics, phosphorylation

Publications

No publications provided. Once you do, you will see displayed a publication timeline here for all publications.


Email:randy.blakely@vanderbilt.edu
Phone:(615) 936-1700
Fax:(615) 936-3745
Office Address
(Default) address 465 21st Avenue South
7150 MRB III
Nashville, TN United States 37232